The first question needing an answer is, "What is Male Pattern Baldness"? We see this every day in our own homes and in public, yet we may not specifically know that it is the loss of hair from the front hairline across the skull to the crown of the head, leaving a fringe of hair around the head and above the ears, no doubt reminding everybody of a tonsured monk. Alopecia is the falling out of the hair as a gradual process. Now, the reason hair falls out is the mystery, at least it was until the research team of Dr. George Cotsarelis, MD, of the University of Pennsylvania, produced the results of his latest research, and reported in Science Translational Medicine.
He found that the bare skin of the scalp in men with hair falling out had elevated levels of prostaglandin D2, compared with scalp tissue that is covered with hair from another part of the head. The hairy parts of the head have less prostaglandin than the smooth parts.. Prostaglandin slows or stops the growth of hair. Using mice and human hair follicles, prostaglandin D2 was applied topically to the smooth parts with the result that hair growth was inhibited and this was effected through a receptor, GPR44. Prostaglandin D2 was about three times higher in the smooth areas than in the hairy parts of the head.
Characteristic of the steps of baldness in humans, the mice who had applied levels of prostaglandin in their skin for purposes of the study, lost their hair, their follicles got smaller and the sebaceous gland got larger.
This team of researchers feels that GPR44 could be a therapy to be worked with in the future to end the curse of baldness, and they could apply drugs that block GPR44 receptor, but they do not yet know whether this condition would allow the hair to grow again when presented with baldness, or if prevention of baldness entirely would occur. They are not sure that inhibiting the receptor would affect humans. We should remember also that testosterone and genetics are mixed with the other factors of prevention and cure; these two factors cause a minimization of the follicles, which become so tiny that they are not visible to the naked eye.
Prostaglandins are found in many human bodily functions and the team claims it was a shock to find that PGD2 was an inhibitor of hair growth while F2alpha prostaglandin proliferates hair growth, as this protein controls cell growth and dilates smooth muscle tissue.
The author of the above study states that they look forward to an effective treatment for the scalp in the form of a cream that would allow the hair to grow. This would be available in approximately five years
Here is a condition that strikes 8 out of 10 men under 70 whose self esteem disappeared along with his hair. Most people have accepted it as a condition of our time; yet others have joined the ranks of people who love the smooth and shiny look of a man with baldness, so they have deliberately shaved their heads and begin to take on the aura of "Mr. T". (This must be a terrific job to keep the head shaved properly, or maybe they should begin to use a cream that stops hair growth and avoids tedious shaving).
Margaret Heaps is a native born Californian who sees life as not long enough to fit everything in. She has grass roots in Petaluma, California and Nicasio, California, where her great grandfather bought land from gold that he mined in the Gold Rush of 1848 and created a high yield dairy farm. With this background legacy, she married and raised six boys, went back to school and became a registered nurse; this was her profession for many years. Now that she has retired, her energy level still high, she has undertaken to build and market a new website: www.fxallbeauty.info
Male Pattern Baldness Cure Almost Ready
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